Post Translational Modifications can be illustrated via everyday scenarios! For example, cars:
The factory model in beautiful and autumnal orange [protein translated from the mRNA transcribed from DNA], can be modified with aftermarket components and paint [Post Translational Modifications].
The addition of the colour red and an enhanced ram scoop and fins certainly adds a dash of panache to any factory standard model.
Feel the speed and migrate over the landscape in this fierce vehicle! [PTM which enhances migration and growth]
The addition of stealthy black and a discreet “cherry top” gives the factory model makes one sit up and say “yes officer!”
For those interested in law and order and the surveillance of one’s own turf, the cherry top adds a classic feel! [PTM which enhances immune activity]
A coat of 80’s pastel and a topping of a message board draws in all the local Ts, NKs, and Macs!
Nothing draws the eye like a bright electronic billboard! Turn your vehicle into a mobile advertising platform but, careful you don’t draw the ire of the surveilling cherry tops! [PTMs makes great neo-antigens!]
Perhaps a subdued pinkish fuschia that brings the posse together and a nice tear drop caravan to contain them all?
Sometimes it takes a village! Bring your kinase and phosphatase friends and we can all complex together! [PTMs can encourage protein complexing and alter downstream signaling]